Skin microbiota analysis in human 3D skin models—“Free your mice”
نویسندگان
چکیده
منابع مشابه
Matriptase-deficient mice exhibit ichthyotic skin with a selective shift in skin microbiota.
Suppressor of tumorigenicity 14 (St14) encodes matriptase, a serine protease, which regulates processing of profilaggrin to filaggin in vivo. Here, we report that transgenic mice with 1% of wild-type St14 levels (St14(hypo/-)) display aberrant processing of profilaggrin and model human ichthyotic skin phenotypes. Scaling of the skin appears at 1 week of age with underlying epidermal acanthosis ...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2020
ISSN: 0906-6705,1600-0625
DOI: 10.1111/exd.14164